Idiopathic generalized anhidrosis: A feature of panautonomic failure

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Idiopathic generalized anhidrosis: a feature of panautonomic failure.

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Generalized anhidrosis.

A nhidrosis is defined as a condition where perspiration does not occur despite adequate and sufficient impulse. 1 This condition may be encountered as localized or diffuse through the whole body. The amount of perspiration caused by temperature, pharmacological agents, and other factors may differ inter-personally. Generalized anhidrosis may be as a result of blockage of the canals of the pers...

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Investigation of antimuscarinic receptor autoantibodies in patients with acquired idiopathic generalized anhidrosis.

OBJECTIVE The autoimmune mechanism is considered to play an important role in the development of acquired idiopathic generalized anhidrosis (AIGA), and muscarinic M3 receptors (M3Rs) on eccrine glands are possible autoimmune targets. We investigated the existence of autoantibodies against M3Rs in AIGA patients. METHODS We immunostained M3R-expressing cultured cells with the serum of 12 AIGA p...

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Acquired generalized anhidrosis associated with lymphocytic infundibuloneurohypophysitis.

Acquired idiopathic generalized anhidrosis (AIGA) has an acute or insidious onset without additional symptoms. There may be eccrine gland dysfunction, and the beneficial effects of corticosteroids lend support to an autoimmune etiology.1,2 Lymphocytic infundibuloneurohypophysitis (LIN) is an inflammatory disorder that can result in central diabetes insipidus (DI); histologic findings showing in...

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Mr J.J., a 32-year-old Iraqi presented for investigation of anhidrosis. In 1967 he first developed a pruritic erythroderma with exfoliation, alopecia, nail loss and mucosal ulceration. There was no history of drug ingestion. Recovery was gradual. Since 1968 the patient has been unable to sweat. As a result he is heat intolerant, with 10 min in a hot environment causing palpitation, headache and...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology, Venereology and Leprology

سال: 2008

ISSN: 0378-6323

DOI: 10.4103/0378-6323.42927